Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases
نویسندگان
چکیده
منابع مشابه
Synthesis of selenomethylene-locked nucleic acid (SeLNA)-modified oligonucleotides by polymerases.
Enzymatic recognition of SeLNA nucleotides was investigated. KOD XL DNA polymerase was found to be an efficient enzyme in primer extension reactions. Polymerase chain reaction (PCR) amplification of SeLNA-modified DNA templates was also efficiently achieved by Phusion and KOD XL DNA polymerases.
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ژورنال
عنوان ژورنال: Chemical Communications
سال: 2012
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c2cc36464f